Analysis of C5a-mediated chemotaxis by lentiviral delivery of small interfering RNA
نویسندگان
چکیده
منابع مشابه
Analysis of C5a-mediated chemotaxis by lentiviral delivery of small interfering RNA.
Immune cells respond to chemotactic signals by means of G protein-coupled receptors. Attempts to elucidate the function of specific G protein family members in these responses is complicated by redundancy among the different G protein isoforms. We have used lentiviral-based RNA interference to eliminate expression of specific G protein subunits selectively in J774A.1 mouse macrophages. The chem...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2003
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0307549100